n-Octyl-ß-D-glucopyranoside (min. 99.0% TLC)

Octyl glucoside (n-octyl-β-D-glucoside) is a detergent frequently used to solubilise integral membrane proteins for studies in biochemistry. It has become one of the most important detergents for purification of membrane proteins because it generally does not denature the protein and can readily be removed from final protein extracts. Above its critical micelle concentration of 0.7%, it was noted as the best detergent for improving selectivity of immunoprecipitation of phosphotyrosine modified proteins. This detergent has also been shown to rapidly inactivate infective HIV at concentrations above its CMC (about 0.7% (w/v)).