S-Pam3Cys-SKKKK

Triacyl-Lipopeptid. The synthetic, triacylated lipopeptides represent the N-terminal lipohexadecapeptides, Pam3Cys-AA15, of bacterial lipoproteins. Names of lipoproteins and origin are indicated. For a complete list of all lipoproteins see attachement. Pam3Cys-SKKKK is the mostly used synthetic analogue of naturally occurring lipoproteins and often described in literature as reference compound for TLR2/1 activation. Pam3Cys-SKKKK is provided as stereochemically defined compounds and as mixture of stereoisomers. Additionally, labelled analogues are available. The peptide is delivered as hydrochloric acid salt!

The C-terminal COOH and the NH2 groups in the side chains of the four lysines are available for modification but can not be addressed specifically. Conjugation will lead to a mixture of products. If a specific conjugation to e.g. the side chain of the C-terminal lysine is required, please inquire for custom specific lipopeptide synthesis. Dependent on the compound which should be conjugated we might be able to offer it also from stock (e.g. biotinylation or dye labelled lipopeptides (P2207 >, P2209 >, P2211 >).