stable Glutamine



Order number: C4297.0050

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CAS-Nr: 121574-43-4

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N-acetyl-L-alanyl-L-glutamine (stable glutamine) for cell culture. L-glutamine is an essential... more
Product information "stable Glutamine"

N-acetyl-L-alanyl-L-glutamine (stable glutamine) for cell culture. L-glutamine is an essential amino acid that is essential for cell growth. While normal L-glutamine undergoes autohydrolysis and is therefore not stable in solution, it can be substituterd by the addition of stable N-acetyl-L-alanyl-L-glutamine which guarantees cell culture medium still containing "L-Glutamine" even after 2 years storage. N-acetyl-L-alanyl-L-glutamine is cleaved by cellular aminopeptidases into alanine and glutamine, providing the cell with the necessary supply of L-glutamine for growth.

Mechanism:
When cells are cultured in N-acetyl-L-alanyl-L-glutamine containing media, the cells gradually release aminopeptidases which hydrolyze the dipeptide, slowly releasing L-alanine and L-glutamine into the culture medium. L-glutamine and L-alanine can then be taken up by the cells and used for protein production or in the TCA cycle. This mechanism can be compared to the fed-batch culture strategy in which L-glutamine is continuously fed into the culture but kept at a low concentration. The result is an efficient energy metabolism and a high growth yield without excess ammonia.

More products around "stable Glutamine"
Specifications: Assay: min. 98% (HPLC) C10H17N3O5 MW = 259.2 g/mol Pyrogen test: corresponds more
 

Technical Data:

Specifications:
Assay: min. 98% (HPLC)
C10H17N3O5
MW = 259.2 g/mol
Pyrogen test: corresponds

application:

amino acid and vitamine powder supplements for cell culture

Sicherheits Hinweise / Safety

Klassifizierungen / Classification

CAS-Nr: 121574-43-4
eclass-Nr: 32-16-08-01
Dokumente - Protokolle - Downloads more

Dokumente - Protokolle - Downloads

Here you will find information and further literature on stable Glutamine. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.

 
 
 
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