HighPure Propidium iodide

Propidium iodide chemical structure


Order number: M3181.0025

Shipping: shipped at RT, store at +2°C to +8°C
CAS-Nr: 25535-16-4

Delivery time: 3- 8 working days
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€44.93 *

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Product information "HighPure Propidium iodide"

HighPure Propidium iodide (3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide) for selective labeling of DNA in dead cells as cell membrane integrity excludes propidium iodide from staining viable and apoptotic cells. Propidium iodide may be used in tumor diagnosis flow cytometry to evaluate cell viability when used with other dyes that stain viable cells or cells that are in early apoptosis process. Can also be used for the study of micronuclear morphology of protozoa.

Propidium iodide can be excited by light with wavelenghts in the visible range and bleaches slowly, having clear advantages over DAPI.

CAUTION: Potent carcerogenic agent. Valet G. et al. (1987) Blut 49, 37-43. Fluorescent stain for nucleic acids. At a concentration of 1 µg/mL, probably all DNA binding sites are saturated.

More products around "HighPure Propidium iodide"
Specifications: Assay (HPLC): min. 95% Absorption maximum: 530 - 540nm Formula: C27H34I2N4 MW... more
 

Technical Data:

Specifications:
Assay (HPLC): min. 95%
Absorption maximum: 530 - 540nm
Formula: C27H34I2N4
MW = 668.4 g/mol

application:

For apoptosis research. Propidium iodide (PI) is a popular red-fluorescent nuclear and chromosome counterstain. Since propidium iodide is not permeant to live cells, it is also commonly used to detect dead cells in a population.

Sicherheits Hinweise / Safety

H-Sätze: H315, H319, H335
GHS-Symbole: GHS07
R-Sätze: R36/37/38
Gefahrstoffkürzel: Xi

Klassifizierungen / Classification

EC-Nr: 247-081-0
CAS-Nr: 25535-16-4
eclass-Nr: 32-16-04-05
Dokumente - Protokolle - Downloads more

Dokumente - Protokolle - Downloads

Here you will find information and further literature on HighPure Propidium iodide. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.

 
 
 
Literatur .... more

Referenzen..

Hier finden Sie Artikel und Literaturzitate, in denen die Autoren auf die hohe Qualität dieses Genaxxonprodukts vertrauen.
Listed below are articles and references, in which the authors trust in the high quality of this Genaxxon product.

Quelle/Source: NCBI PubMed >

Innate extracellular vesicles from melanoma patients suppress β-catenin in tumor cells by miRNA-34a
Jung-Hyun Lee, Jochen Dindorf, Martin Eberhardt, Xin Lai, Christian Ostalecki, Nina Koliha, Stefani Gross, Katja Blume, Heiko Bruns, Stefan Wild, Gerold Schuler, Julio Vera, Andreas S Baur
Life Sci Alliance. 2019 Apr; 2(2): e201800205. Published online 2019 Mar 7. doi: 10.26508/lsa.201800205
PMCID: PMC6406044

HIV Activates the Tyrosine Kinase Hck to Secrete ADAM Protease-Containing Extracellular Vesicles

J.-H. Lee, C. Ostalecki, Z. Zhao, T. Kesti, H. Bruns, B. Simon, T. Harrer, K. Saksela, A.S. Baur

EBioMedicine. 2018 Feb; 28: 151–161. Published online 2018 Jan 4. doi: 10.1016/j.ebiom.2018.01.004
PMCID: PMC5836510

HIV Nef- and Notch1-dependent Endocytosis of ADAM17 Induces Vesicular TNF Secretion in Chronic HIV Infection

Christian Ostalecki, Sebastian Wittki, Jung-Hyun Lee, Miriam M. Geist, Nadine Tibroni, Thomas Harrer, Gerold Schuler, Oliver T. Fackler, Andreas S. Baur

EBioMedicine. 2016 Nov; 13: 294–304. Published online 2016 Oct 19. doi: 10.1016/j.ebiom.2016.10.027

PMCID: PMC5264432

HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection

Jung-Hyun Lee, Stephan Schierer, Katja Blume, Jochen Dindorf, Sebastian Wittki, Wei Xiang, Christian Ostalecki, Nina Koliha, Stefan Wild, Gerold Schuler, Oliver T. Fackler, Kalle Saksela, Thomas Harrer, Andreas S. Baur

EBioMedicine. 2016 Apr; 6: 103–113. Published online 2016 Mar 3. doi: 10.1016/j.ebiom.2016.03.004

PMCID: PMC4856776

Improved assessment of frozen/thawed mouse spermatozoa using fluorescence microscopy

Ann-Kathrin Diercks, Heinrich F. Bürgers, Anna Schwab, Johannes Schenkel

J Vet Sci. 2012 Sep; 13(3): 315–322. Published online 2012 Sep 20. doi: 10.4142/jvs.2012.13.3.315

PMCID: PMC3467408