Lucigenin
Order number: S5552.0002
Shipping: shipped at RT, store at +2°C to +8°CCAS-Nr: 2315-97-1
Delivery time: 3- 8 working days
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Lucigenin is a chemoluminescent probe used for the detection of peroxides in biological systems / cells. Upon single-electron reduction of Lucigenin Lucigenin presents an amplified chemiluminescence which is measurable and can be correlated to the respective amount of reactive radical species present in the system. This approach can be used to probe the natural generation of these species as well as the natural functioning of superoxide dismutase and other enzymes responsible for scavenging radicals.
The chemical name for Lucigenin bis-N-methylacridinium nitrate. The substance exhibits a bluish-green fluorescence.
References:
M. Kervinen et al.; Anal. Biochem. 324, 45 (2004)
M. Kanemitsu et al.; Anal. Chim. Acta 403, 125 (2000)
L.J. Kricka et al.; Methods Enzymol. 305, 333 (2000)
K. Faulkner et al.; Free Radic. Biol. Med. 15, 447 (1993)
A. Ingvarsson et al.; Anal. Chem. 60, 2047 (1988)
P. Corbisier et al.; J. Anal. Biochem. 164, 240 (1987)
Technical Data:
Specifications:
Assay: min. 98% (Elemental Analysis)
Identity determined by: NMR/IR
Appearance: off-white to brownish powder
Fluorescence: λex 369 nm; λem 505 nm (water); λex 455 nm; λem 505 nm (DMSO)
Solubility: acetic acid (appr. 10mg/mL), DMSO (appr. 12mg/mL). Slightly soluble in water (appr. 8mg/mL) and Ethanol (appr. 0.5mg/mL)
C28H22N4O6
MW = 510.50 g/mol
Sicherheits Hinweise / Safety
Klassifizierungen / Classification
EC-Nr: 219-023-4CAS-Nr: 2315-97-1
eclass-Nr: 32-16-04-05
Dokumente - Protokolle - Downloads
Here you will find information and further literature on Lucigenin. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.
