rec. Rat Interleukin-12 (rrIL-12)
Order number: C6087.0002
Shipping: shipped at RT, stored at -20°C Ready to ship today,
Delivery time 1-3 workdays
*Prices plus VAT plus shipping costs
Interleukin 12 (IL-12) is a cytokine with important regulatory functions bridging innate and adaptive immunity. It has been proposed as an immune adjuvant for vaccination therapy of infectious diseases and malignancies. The inflammatory properties of IL-12 play an important role in the adjuvant. Interleukin 12 (IL-12) is a proinflammatory cytokine composed by two chains, p40 and p35.It plays a key role in the promotion of a Th1 immune response in the gastrointestinal mucosa. An enhanced expression of IL-12 mRNA in gastric mucosa has been reported in individuals infected by Helicobacter pylori. Recombinant rat Interleukin-12 produced in Sf9 insect cells is a glycosylated disulfide linked heterodimeric polypeptide of 503 amino acids and a molecular weight of 70 kDa comprised of disulfide-bonded 35 kDa (p35) and 40 kDa (p40) subunits. Synonyms: NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12.
Technical Data:
Purity: >95.0% (SDS-PAGE). Less than 1% dimers and aggregates. Sterile Filtered White lyophilized (freeze-dried) powder. Endotoxin: Less than 0.1 ng/µg (IEU/µg) rrIL-12.
Source
Sf9-cells/baculo virusSicherheits Hinweise / Safety
Klassifizierungen / Classification
eclass-Nr: 32-16-04-90Dokumente - Protokolle - Downloads
Here you will find information and further literature on rec. Rat Interleukin-12 (rrIL-12). For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.