Cytokines & Growth Factors

Cytokines are a heterogeneous group of proteins and peptides which influence at very low concentrations as so-called second messengers activities of cells and tissues, such as growth, proliferation and differentiation. Many of them have an immunomodulating function. Cytokines also mediate interactions between cells and regulate extracellular processes.

We offer a wide selection of recombinant cytokines and growth factors from the main groups:

- Interferons > (IF of mouse, human, rat and pig): stimulate the cells to form defense substances
- Interleukins > (mouse, human, rat and pig): for communication between leukocytes
- Colony Stimulating Factors > (CSF) and other growth factors such as Vascular Endothelial Growth Factors (VEGF), or Growth Hormones (GH)
- Tumor Necrosis Factors > (TNF)

Cytokines are a heterogeneous group of proteins and peptides which influence at very low concentrations as so-called second messengers activities of cells and tissues, such as growth,... read more »
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Cytokines & Growth Factors

Cytokines are a heterogeneous group of proteins and peptides which influence at very low concentrations as so-called second messengers activities of cells and tissues, such as growth, proliferation and differentiation. Many of them have an immunomodulating function. Cytokines also mediate interactions between cells and regulate extracellular processes.

We offer a wide selection of recombinant cytokines and growth factors from the main groups:

- Interferons > (IF of mouse, human, rat and pig): stimulate the cells to form defense substances
- Interleukins > (mouse, human, rat and pig): for communication between leukocytes
- Colony Stimulating Factors > (CSF) and other growth factors such as Vascular Endothelial Growth Factors (VEGF), or Growth Hormones (GH)
- Tumor Necrosis Factors > (TNF)

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human chorionic gonadotropin - hCG Human Chorionic Gonadotropin (hCG)
Human chorionic gonadotropin (hCG) is a peptide hormone produced in pregnancy, that is made by the embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). Its role is to prevent the disintegration of the...
From €150.26 *
Human flt3-ligand, rec. Human flt3-ligand, rec.
Recombinant human Flt3-Ligand produced in E.Coli is a non-glycosylated, polypeptide chain of 155 amino acids and a molecular mass of approximately 17.6kDa. Flt3 ligand (FL) is a hematopoietic four helical bundle cytokine. It is...
From €145.00 *
Kinetin - chemical structure Kinetin - 6-Furfurylaminopurine
Kinetin is an analogue to Zeatin, an adenine-type cytokinin phytohormone that is used in plant culture media such as Murashige & Skoog media in conjunction with auxins such as indole-3-acetic acid (IAA), Indole-3-butyric acid (IBA),...
From €79.50 *
Rat IFN-gamma, rec. Rat IFN-gamma, rec.
The major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II...
From €170.89 *
rbFGF-b rbFGF-b
FGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and...
From €154.75 *
rec. Human Epidermal Growth Factor (rHuEGF) rec. Human Epidermal Growth Factor (rHuEGF)
Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. EGF is believed to exist as a...
From €164.52 *
rec. human FGF-8 rec. human FGF-8
Recombinant human FGF-8 produced in E.Coli is a single, non-glycosylated, polypeptide of 194 amino acids and a MW of 22.5 kDa. GF8 is part of the fibroblast growth factor family. FGF family members have wide mitogenic and cell survival...
From €165.50 *
FGF-beta - Fibroblast Growth Factor 2 rec. Human Fibroblast Growth Factor-basic -...
Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic...
From €125.00 *
rec. Human Granulocyte Colony Stimulating Factor - (rHuG-CSF) rec. Human Granulocyte Colony Stimulating...
GCSF is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for the GCSF gene....
From €125.00 *
granulocyte macrophage colony stimulating factor - GM-CSF rec. Human Granulocyte Macrophage Colony...
Human GM-CSF produced in E.Coli is a single, non-glycosylated, polypeptide chain of 127 amino acids and a molecular mass of 14,477 Dalton. The ED50 as determined by the dose-dependant stimulation of the proliferation of human TF-1 cells...
From €125.00 *
rec. Human Growth Hormone-20K (rHuGH-20K) rec. Human Growth Hormone-20K (rHuGH-20K)
Recombinant Human GH-20K produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 177 amino acids and having a molecular mass of 20,322 Dalton. rHugH-20K is purified by proprietary chromatographic techniques.
From €178.83 *
rec. Human Hepatocyte Growth Factor (rHuHGF) rec. Human Hepatocyte Growth Factor (rHuHGF)
Recombinant Human HGF produced in Baculovirus is a heterodimer, non-glycosylated, polypeptide chain consisting an a-chain of 463 amino acids and b-chain of 234 having a total molecular mass of 80,017 Dalton. Hepatocyte Growth Factor...
From €170.89 *
rec. Human Insulin-Like Growth Factor I (rHulGF-I) rec. Human Insulin-Like Growth Factor I (rHulGF-I)
The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250)....
From €145.75 *
rec. Human Interferon-Gamma (rHulFN-g) rec. Human Interferon-Gamma (rHulFN-g)
Recombinant Human IFN-g produced in E.Coli is a single, non-glycosylated, polypeptide chain of 144 amino acids and amolecular mass of 16,879 Dalton. IFN-gamma is produced by lymphocytes activated by specific antigens or mitogens....
From €145.00 *
rec. human Interleukin 12 - rHuIL-12 rec. human Interleukin 12 - rHuIL-12
IL-12 is a heterodimeric cytokine that stimulates the production of interferon gamma from T-cells and natural killer cells, and also induces differentiation of Th1 helper cells. IL-12 is an initiator of cell-mediated immunity....
From €170.89 *
rec. human Interleukin 13 (rHuIL-13) rec. human Interleukin 13 (rHuIL-13)
IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype...
From €145.00 *
rec. Human Interleukin-1 alpha (rHuIL-1 alpha) rec. Human Interleukin-1 alpha (rHuIL-1 alpha)
Recombinant Human IL-1a produced in E.Coli is a non-glycosylated, Polypeptide chain containing 159 amino acids and having a molecular mass of 18,022 Dalton. rHuIL-1a is purified by proprietary chromatographic techniques. The ED50 as...
From €125.00 *
rec. Human Interleukin-10 (rHuIL-10) rec. Human Interleukin-10 (rHuIL-10)
IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags,...
From €194.93 *
rec. Human Interleukin-11 (rHuIL-11) rec. Human Interleukin-11 (rHuIL-11)
Recombinant Human IL-11 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19,256 Dalton. The ED50 as determined by the dose-dependant stimulation of the...
From €164.52 *
rec. Human Interleukin-15 (rHuIL-15) rec. Human Interleukin-15 (rHuIL-15)
Description: Recombinant Human IL-15 produced in E.Coli is a single, non-glycosylated, polypeptide of 114 amino acids and a molecular mass of 12.8 kDa. The protein encoded by this gene is a cytokine that regulates T and natural killer...
From €145.00 *
rec. Human Interleukin-2 (rHuIL-2) rec. Human Interleukin-2 (rHuIL-2)
Recombinant Human IL-2 produced in E.Coli is a single, non-glycosylated mutein (variant form) of human IL-2 polypeptide chain containing 133 amino acids and having a molecular mass of 15,385 Dalton. The Genaxxon rHuIL-2 is Des N-Terminal...
From €164.52 *
rec. Human Interleukin-20 (rHuIL20) rec. Human Interleukin-20 (rHuIL20)
The newly discovered cytokine interleukin-20 (IL-20) is structurally related to IL-10, yet it appears to be an autocrine factor for keratinocytes that regulates their participation in inflammation. IL-20 is fully biologically active when...
From €170.89 *
rec. Human Interleukin-22 (rHuIL22) rec. Human Interleukin-22 (rHuIL22)
From €170.89 *
rec. Human Interleukin-3 (rHuIL-3) rec. Human Interleukin-3 (rHuIL-3)
Recombinant Human IL3 produced in E.Coli is a single, non-glycosylated polypeptide chain of 133 amino acids and a molecular mass of 15,000 Dalton. IL3 is a potent growth promoting cytokine. This cytokine is capable of supporting the...
From €145.00 *
rec. Human Interleukin-5 (rHuIL-5) rec. Human Interleukin-5 (rHuIL-5)
Rec. human Interleukin-5 produced in E.Coli is a dimeric, non-glycosylated polypeptide chain of two 113 amino acids chains, with a molecular mass of 26522.84 Dalton. The protein encoded by this gene is a cytokine that acts as a growth...
From €145.00 *
rec. Human Interleukin-6 (rHuIL-6) rec. Human Interleukin-6 (rHuIL-6)
Recombinant Human IL-6 produced in E.Coli is a single, non-glycosylated polypeptide chain of 184 amino acids and a molecular mass of 21,000 Dalton. IL-6 is a cytokine with a wide variety of biological functions: it plays an essential...
From €145.00 *
rec. Human Interleukin-7 (rHuIL-7) rec. Human Interleukin-7 (rHuIL-7)
Recombinant Human IL-7 produced in E.Coli is a single, non-glycosylated polypeptide of 172 amino acids and a molecular mass of 17,412 Dalton. The ED50 as determined by the dose-dependant stimulation of murine IXN/2B cells is
From €145.00 *
rec. Human Interleukin-9 (rHuIL-9) rec. Human Interleukin-9 (rHuIL-9)
From €232.48 *
rec. Human Neurotrophin-3 (rHuNT-3) rec. Human Neurotrophin-3 (rHuNT-3)
NT3 a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the...
From €164.52 *
rec. Human Placental Growth Hormone (rHuPGH) rec. Human Placental Growth Hormone (rHuPGH)
Recombinant Human PGH produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 192 amino acids and having a molecular mass of 22,367 Dalton. rHuPGH is purified by proprietary chromatographic techniques.
From €479.27 *
rec. Human Platelet-derived Growth Factor BB (rHuPDGF-BB) rec. Human Platelet-derived Growth Factor BB...
Recombinant Human PDGF-BB produced in E.Coli is a double, non-glycosylated, polypeptide chain containing 109 amino acids and having a molecular mass of 24,525 Dalton. The ED50, calculated by the dose-dependant proliferation of murine...
From €170.89 *
rec. Human Stem Cell Factor (rHuSCF) rec. Human Stem Cell Factor (rHuSCF)
Recombinant Human SCF produced in E.Coli is a single, non-glycosylated polypeptide chain of 164 amino acids and a molecular mass of 18,409 Dalton. Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also...
From €145.00 *
rec. Human Stromal Cell-Derived Factor-1 alpha (rHuSDF-1a) rec. Human Stromal Cell-Derived Factor-1 alpha...
Recombinant Human IL-SDF-1a produced in E.Coli is a non-glycosylated, polypeptide chain of 68 amino acids and having a molecular mass of 8,008 Dalton. SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine...
From €135.91 *
rec. human vascular epidermal growth factor - VEGF rec. Human Vascular Endothelial Growth Factor...
Description: Vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although...
From €125.00 *
rec. mouse Interleukin-2 (rmIL-2) rec. mouse Interleukin-2 (rmIL-2)
IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin-4 (IL-4) and interleukin-7...
From €145.00 *
rec. Murine Granulocyte Macrophage Colony Stimulating Factor (rmGM-CSF) rec. Murine Granulocyte Macrophage Colony...
Recombinant murine GM-CSF produced in E.Coli is a single, non-glycosylated, polypeptide chain of 125 amino acids and a molecular mass of 14,285 Dalton. The ED50 as determined by the dose-dependant stimulation of the proliferation of...
From €164.75 *
rec. Murine Insulin-Like Growth Factor I (rmlGF-I) rec. Murine Insulin-Like Growth Factor I (rmlGF-I)
Recombinant murine IGF-I produced in E.Coli is a single, non-glycosylated, polypeptide chain of 70 amino acids and a molecular mass of 7,600 Dalton. The ED50, calculated by the dose-dependant proliferation of murine BALB\C 3T3 cells...
From €164.52 *
rec. Murine Interleukin-1 beta (rmIL-1b) rec. Murine Interleukin-1 beta (rmIL-1b)
Recombinant Murine IL-1 b produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17,500 Dalton. rHuIL-1b is purified by proprietary chromatographic techniques. The specific...
From €170.89 *
rec. Murine Tumor Necrosis Factor-alpha (rmTNF-a) rec. Murine Tumor Necrosis Factor-alpha (rmTNF-a)
Recombinant murine TNF-a produced in S.Lividans is a single, glycosylated, polypeptide chain of 156 amino acids and a molecular mass of 17,301 Dalton. The ED50 as determined by the cytolysis of murine L929 cells in the presence of...
From €164.52 *
rec. Ovine Growth Hormone (rOGH) rec. Ovine Growth Hormone (rOGH)
Recombinant Ovine Growth Hormone produced in E.Coli is a single, non-glycosylated polypeptide chain containing 200 amino acids and having a molecular mass of 22,015 Dalton. GH is a member of the somatotropin/prolactin family of hormones...
From €178.83 *
rec. Rat Insulin-Like Growth Factor I (rrlGF-I) rec. Rat Insulin-Like Growth Factor I (rrlGF-I)
The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250)....
From €170.89 *
rec. Rat Interleukin 4 - rrIL-4 rec. Rat Interleukin 4 - rrIL-4
Recombinant Rat Interleukin-4 (rrIL4) is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions...
From €170.89 *
rec. Rat Interleukin-1 alpha (rrIL-1a) rec. Rat Interleukin-1 alpha (rrIL-1a)
A soluble factor produced by monocytes, macrophages, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the...
From €125.00 *
rec. Rat Interleukin-1 beta (rrIL-1b) rec. Rat Interleukin-1 beta (rrIL-1b)
A soluble factor produced by monocytes, macrophages, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the...
From €170.89 *
rec. Rat Interleukin-12 (rrIL-12) rec. Rat Interleukin-12 (rrIL-12)
Interleukin 12 (IL-12) is a cytokine with important regulatory functions bridging innate and adaptive immunity. It has been proposed as an immune adjuvant for vaccination therapy of infectious diseases and malignancies. The inflammatory...
From €170.89 *
rec. Rat Interleukin-13 (rrIL-13) rec. Rat Interleukin-13 (rrIL-13)
IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype...
From €170.89 *
rec. Rat Interleukin-15 (rrIL15) rec. Rat Interleukin-15 (rrIL15)
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor...
From €170.89 *
rec. Rat Interleukin-18 (rrIL-18) rec. Rat Interleukin-18 (rrIL-18)
Interleukin-18 is a member of the interleukin-1 family of cytokines with pro-inflammatory and tumor-suppressive properties. Its ability to potently enhance the production of interferon-gamma indicates in particular the crucial function...
From €170.89 *
Recombinant Human IL-18 (rHuIL-18) Recombinant Human IL-18 (rHuIL-18)
rec. human Interleukin-18 produced in E.Coli is a single, non-glycosylated polypeptide chain of 157 amino acids and a molecular mass of 18302 Dalton. IL-18 is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production...
From €125.00 *
recombinant human LIF - rhuLIF recombinant human LIF - rhuLIF
Rec. human Leukemia Inhibitory Factor produced in E.Coli is a single, non-glycosylated, polypeptide of 181 amino acids with a molecular mass of 20kDa. Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term...
From €170.89 *
Recombinant Mouse IL-18 (rmIL-18) Recombinant Mouse IL-18 (rmIL-18)
rec. murine Interleukin-18 produced in E.Coli is a single, non-glycosylated polypeptide chain of 178 amino acids (36-192 a.a.) and a molecular mass of 20.4 kDa. IL-18 is a proinflammatory cytokine. This cytokine can induce the IFN-gamma...
From €170.63 *
rHuM-CSF rHuM-CSF
Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the...
From €170.89 *
rHuman Growth Hormone (rHuGH) rHuman Growth Hormone (rHuGH)
GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are...
From €170.89 *
rHuTPO rHuTPO
Recombinant human Thrombopoietin (rHuTPO) expressed and isoltated from HEK cells is a single, non-glycosylated polypeptide of 332 amino acids and a molecular mass of 78-84 kDa depending on the glycosylation. Thrombopoietin is a...
From €145.00 *
rmEGF rmEGF
Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to...
From €154.75 *
rmFGF-b rmFGF-b
Recombinant Mouse Fibroblast Growth Factor-basic (FGF-2) is produced in E.Coli as a single, non-glycosylated, polypeptide of 146 amino acids and a molecular mass of 16.3kDa. GF-basic is a member of the fibroblast growth factor (FGF)...
From €154.75 *
rmIL-10 rmIL-10
Recombinant Mouse Interleukin-10
From €170.89 *
rmIL-4 rmIL-4
Recombinant Murine Interleukin-4
From €170.89 *
rmIL-6 rmIL-6
Interleukin-6 is a potent pro-inflammatory cytokine primarily produced by activated T cells and an assortment of other cells including endothelial cells and macrophages. IL-6 affects B and T lymphocytes and has been shown to have a role...
From €170.89 *
rmIL-7 rmIL-7
Recombinant Murine Interleukin-7
From €170.89 *
rmIL-9 rmIL-9
Recombinant Murine Interleukin-9
From €170.89 *
rmLIF - rec. Leukemia Inhibitory Factor rmLIF - rec. Leukemia Inhibitory Factor
Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron...
From €145.00 *
rmM-CSF rmM-CSF
Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the...
From €170.89 *
rmTPO rmTPO
Recombinant mouse TPO produced in E.Coli is a single, non-glycosylated soluble polypeptide of 174 amino acids and a molecular mass of 18704 Dalton. Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidneyt hat...
From €170.89 *
rmVEGF - recombinant Vascular Endothelial Growth Factor Mouse rmVEGF - recombinant Vascular Endothelial...
Description: rmVEGF the vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. VEGF activity has been mostly studied on cells of the vascular endothelium, although it does...
From €125.00 *
rpIL-4 rpIL-4
Recombinant Porcine Interleukin-4
From €170.89 *
rrIL-3 rrIL-3
Recombinant Rat Interleukin-3
From €170.89 *
rrIL-5 rrIL-5
Recombinant Rat IL-5
From €170.89 *
rrIL-6 rrIL-6
Recombinant Rat Interleukin-6
From €170.89 *
rrVEGF - recombinant rat VEGF rrVEGF - recombinant rat VEGF
Recombinant Rat Vacular Endothelial Growth Factor
From €170.89 *
Thidiazuron (TDZ) - chemical structure Thidiazuron (TDZ)
Thidiazuron (TDZ) a urea derivative which acts as a cytokinin-active plant growth regulator used in micropropagations to supplement media such as Murashige and Skoog medium. TDZ promotes plant organogenesis (shoot regeneration) and plant...
From €143.33 *
trans-Zeatin - chemical structure trans-Zeatin
Zeatin, a phytohormone derived from adenine, belongs to the family of plant growth hormones called cytokinins. Zeatin promotes growth of lateral buds, stimulates cell division, callus initiation and seed germination. Zeatin is used with...
From €204.75 *