4,5-diaminofluorescein diacetate - DAF-2 DA

4,5-Diaminofluoresceindiacetat - DAF-2 DA


Order number: S5440.0001

Shipping: shipped at RT, store at -20°C, protect from light
CAS-Nr: 205391-02-2

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4,5-diaminofluorescein diacetate (DAF-2 DA) is a highly sensitive probe for the real time... more
Product information "4,5-diaminofluorescein diacetate - DAF-2 DA"

4,5-diaminofluorescein diacetate (DAF-2 DA) is a highly sensitive probe for the real time detection of NO in vivo. Cell permeable.

Application: DAF-2 DA is probably the most successful indicator for nitric oxide. As with other fluorescein diacetates, DAF-2 diacetate is membrane permeant and is deacetylated by intracellular esterases to 4,5-diaminofluorescein (DAF-2). Can be used for the fluorimetric detection of nitric oxide and in fluorescence microscopy to measure realtime changes in nitric oxide levels in vivo.

References:
V.M. Dirsch et al.; Biol. Proc. Online 5, 136 (2003)
N. Nagata et al.; J. Biochem. 125(4), 658 (1999)
H. Kojima et al.; Anal. Chem. 70(13), 2446 (1998)
H. Kojima et al.; Chem. Pharm. Bull. 46, 373 (1998)
H. Kojima et al.; Neuroreport 9, 3345 (1998)

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Our comment on "4,5-diaminofluorescein diacetate - DAF-2 DA"
indicator for nitric oxide DAF-2 diacetate is membrane permeant
Specifications: Purity: >95% (HPLC) Appearance: Off-white powder Identity: determined by... more
 

Technical Data:

Specifications:
Purity: >95% (HPLC)
Appearance: Off-white powder
Identity: determined by NMR
C24H18N2O7
MW = 446.41 g/mol
Fluorescence: λex 491 nm; λem 513 nm
Solubility: soluble in DMSO

application:

fluorimetric detection of nitric oxide and in fluorescence microscopy to measure real-time changes in nitric oxide levels in vivo.

Source

synthetic

Sicherheits Hinweise / Safety

H-Sätze: H302
R-Sätze: R22
Gefahrstoffkürzel: Xn

Klassifizierungen / Classification

CAS-Nr: 205391-02-2
eclass-Nr: 39-21-01-90
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Dokumente - Protokolle - Downloads

Here you will find information and further literature on 4,5-diaminofluorescein diacetate - DAF-2 DA. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.