4,5-diaminofluorescein diacetate - DAF-2 DA

Order number: S5440.0001
Shipping: shipped at RT, store at -20°C, protect from lightCAS-Nr: 205391-02-2
Delivery time: 3- 8 working days
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4,5-diaminofluorescein diacetate (DAF-2 DA) is a highly sensitive probe for the real time detection of NO in vivo. Cell permeable.
Application: DAF-2 DA is probably the most successful indicator for nitric oxide. As with other fluorescein diacetates, DAF-2 diacetate is membrane permeant and is deacetylated by intracellular esterases to 4,5-diaminofluorescein (DAF-2). Can be used for the fluorimetric detection of nitric oxide and in fluorescence microscopy to measure realtime changes in nitric oxide levels in vivo.
References:
V.M. Dirsch et al.; Biol. Proc. Online 5, 136 (2003)
N. Nagata et al.; J. Biochem. 125(4), 658 (1999)
H. Kojima et al.; Anal. Chem. 70(13), 2446 (1998)
H. Kojima et al.; Chem. Pharm. Bull. 46, 373 (1998)
H. Kojima et al.; Neuroreport 9, 3345 (1998)
indicator for nitric oxide DAF-2 diacetate is membrane permeant
Technical Data:
Specifications:
Purity: >95% (HPLC)
Appearance: Off-white powder
Identity: determined by NMR
C24H18N2O7
MW = 446.41 g/mol
Fluorescence: λex 491 nm; λem 513 nm
Solubility: soluble in DMSO
application:
fluorimetric detection of nitric oxide and in fluorescence microscopy to measure real-time changes in nitric oxide levels in vivo.Source
syntheticSicherheits Hinweise / Safety
H-Sätze: H302R-Sätze: R22
Gefahrstoffkürzel: Xn
Klassifizierungen / Classification
CAS-Nr: 205391-02-2eclass-Nr: 39-21-01-90
Dokumente - Protokolle - Downloads
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