TLCK

TLCK from Genaxxon


Order number: M3375.0100

Shipping: shipped at RT, stored at -20°C
CAS-Nr: 4272-74-6

Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.

€69.92 *

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TLCK is an irreversible, specific inhibotor of the Serin-protease Trypsin and inhibits the... more
Product information "TLCK"

TLCK is an irreversible, specific inhibotor of the Serin-protease Trypsin and inhibits the Thrombin-like protease Cerastocytin. Together with the competitive inhibitors benzamidin hydrochlorid or 8M urea Trypsin does not show inhibitiory effects. Chymotrypsin is not inhibited by TLCK. The pH optimum for inhibition through Histidin modification is pH 7.5. Chymotrypsinogen is not inhibited by TLCK. A concentration of 50 µg/mL of TLCK inhibits 100% of the Trypsin like proteinase activity of wheat seat extracts. Besides proteases also protein kinases are inhibited by TLCK. Obviously by the modification of the enzymatic activity centre of the protein kinases.

TLCK solutions are most stable at pH 6.0 at +4°C. TLCK is not stable at pH above 7.0. Therefore stock solutions of 1 mg/mL to 20 mg/mL are prepared with buffer solutions of pH below 6.0. Always pipete shortly before the inhibition experiment. Working solutionsa are: 50 µg/mL to 100 µg/mL.

You will find further protease inhibitors here: Inhibitors >: Pepstatin A >, AEBSF >, Leupeptin >, TLCK >, PMSF >, Bestatine > or Diisopropylphosphorofluoridat (DFP) >.

More products around "TLCK"
Specifications: Assay: min. 99.0% alpha20°C/D, H2O: -6.5° - -8° MP = 163°C - 165°C... more
 

Technical Data:

Specifications:
Assay: min. 99.0%
alpha20°C/D, H2O: -6.5° - -8°
MP = 163°C - 165°C
C14H21ClN2O3S
MW = 369.31 g/mol

Source

synthetic

Sicherheits Hinweise / Safety

H-Sätze: H315, H319, H335
GHS-Symbole: GHS07

Klassifizierungen / Classification

EC-Nr: 224-266-4
CAS-Nr: 4272-74-6
eclass-Nr: 32-16-04-05
Dokumente - Protokolle - Downloads more

Dokumente - Protokolle - Downloads

Here you will find information and further literature on TLCK. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: info@genaxxon.com or phone: +49 731 3608 123.