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Aphidicolin inhibits the growth of eukaryotic cells and certain animal viruses by selectively inhibiting the cellular replication of DNA polymerase II or the viral-induced DNA polymerases. The drug may be useful for controlling excessive cell proliferation in patients with cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells. Aphidicolin is a tool in cell proliferation and differentiation research. Aphidicolin may possibly be used for controlling excessive cell proliferation in cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells.
Assay: min 98%
Appearance: Off-white substance
Soluble: in MeOH, DMSO and Ethanol
MP = 218-220°C
MW = 338.5 g/mol
Toxic, may be carcinogenic. Please wear gloves and mask when handling product. Highly hygroscopic. Sealed under inert gas.
application:Used as specific inhibitor of alpha-type DNA-polymerase (eucaryotic and viral coded).
Sicherheits Hinweise / Safety
Klassifizierungen / ClassificationCAS-Nr: 38966-21-1
Dokumente - Protokolle - Downloads
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