Order number: M3442.0250Shipping: shipped at RT, stored at -20°C
Delivery time: 3- 8 working days
For detailed information on the delivery date, please contact Genaxxon.
Adenosine-3′,5′-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis, eg. in resting human B-lymphocytes. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle.
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor.
W Epstein.; LB Rothman-Denes. Adenosine 3': 5'-cyclic monophosphate as mediator of catabolite repression in Escherichia coli. PNAS.1975, 72, (6), 2300-2304.
CM Szego.; JS Davis. Adenosine 3', 5'-monophosphate in rat uterus: acute elevation by estrogen. PNAS.1967, 58, (4), 1711-1718.
Assay (HPLC): min. 98%
Appearance: white to off-white powder
Identity: determined by 31P- NMR, 1H-NMR, FAB-MS and UV
Solubility: 50mg/mL (H2O)
C10H11N5O6P x Na
MW = 351.19 g/mol
Sicherheits Hinweise / Safety
Klassifizierungen / ClassificationCAS-Nr: 37839-81-9
Dokumente - Protokolle - Downloads
Here you will find information and further literature on Adenosine-3',5'-cyclic monophosphate sodium salt - cAMP. For further documents (certificates with additional lot numbers, safety data sheets in other languages, further product information) please contact Genaxxon biosience at: firstname.lastname@example.org or phone: +49 731 3608 123.