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Produktinformationen "rHuM-CSF"
Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. MCSF induces cells of the monocyte/macrophage lineage. MCSF plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Rec. human Macrophage Colony Stimulating Factor produced in E.coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain of 2 x 159 amino acids and a total molecular mass of 36.8 KD.
Synonyms: Macrophage Colony Stimulating Factor, CSF-1, Lanimostim, MCSF, MGC31930, M-CSF.
Specifications:
Assay: >97% (HPLC)
Sequence of the first five N-terminal amino acids of MCSF: Met-Glu-Glu-Val-Ser.
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