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Product information "Bleomycin sulfate, lyophil. pure"
Group of glycopeptide antibiotics from Streptomyces verticillus with antineoplastic properties by inhibition of DNA synthesis. Bleomycin sulfate is a mixture of bleomycin A2 and bleomycin B2 as the major components. Bleomycin sulfate occurs as a cream-colored, amorphous powder and is very soluble in water and sparingly soluble in alcohol. The potency of bleomycin is assayed microbiologically, the activity of 1 unit of bleomycin is equivalent to the activity of 1mg of bleomycin A2 reference standard. For chemistry and action of bleomycin, see: Umezaw, H. (1980) Med. Chem. 16, 147-66.
Specifications:
Main component is Bacitracin A
Bacteriocidal activity requires divalent cations like Zn++
Source:
Streptomycs verticillusSafety Information:
H Statements:
H351
GHS symbols:
GHS08
Classification:
EC no:
232-925-2
CAS no.:
9041-93-4
eclass no.:
32-19-90-90
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