Lucigenin
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Product information "Lucigenin"
Lucigenin is a chemoluminescent probe used for the detection of peroxides in biological systems / cells. Upon single-electron reduction of Lucigenin Lucigenin presents an amplified chemiluminescence which is measurable and can be correlated to the respective amount of reactive radical species present in the system. This approach can be used to probe the natural generation of these species as well as the natural functioning of superoxide dismutase and other enzymes responsible for scavenging radicals.
The chemical name for Lucigenin bis-N-methylacridinium nitrate. The substance exhibits a bluish-green fluorescence.
References:
M. Kervinen et al.; Anal. Biochem. 324, 45 (2004)
M. Kanemitsu et al.; Anal. Chim. Acta 403, 125 (2000)
L.J. Kricka et al.; Methods Enzymol. 305, 333 (2000)
K. Faulkner et al.; Free Radic. Biol. Med. 15, 447 (1993)
A. Ingvarsson et al.; Anal. Chem. 60, 2047 (1988)
P. Corbisier et al.; J. Anal. Biochem. 164, 240 (1987)
Specifications:
Assay: min. 98% (Elemental Analysis)
Identity determined by: NMR/IR
Appearance: off-white to brownish powder
Fluorescence: λex 369 nm; λem 505 nm (water); λex 455 nm; λem 505 nm (DMSO)
Solubility: acetic acid (appr. 10mg/mL), DMSO (appr. 12mg/mL). Slightly soluble in water (appr. 8mg/mL) and Ethanol (appr. 0.5mg/mL)
C28H22N4O6
MW = 510.50 g/mol
Klassifizierungen / Classification
Documents:
Safety Data SheetCertificate