![CHAPSO; 3-([3-Cholamidopropyl]dimethylammonio)-2-hydroxy-1-propanesulfonate](https://www.genaxxon.com/media/e0/8a/9b/1708287096/m6202_chapso.jpg?ts=1708287096 "m6202_chapso")
Advantages at a glance
- Purity (HPLC): >98%
- Appearance: White solid crystals
- Water: <5%
- Formula: C32H58N2O8S
- MW: 630.87 g/mo
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Product information "CHAPSO - min. 98.0% (HPLC)"
3-[(3-cholamidopropyl)-dimethylammonio]-2-hydroxy-1-propanesulphonate (CHAPSO) is a zwitterionic detergent and is used as a non-denaturing buffering agent.
CHAPSO has similar properties to CHAPS, but possesses an additional hydroxyl group (-OH), making it more polar and more soluble.
CHAPSO is frequently used for the solubilisation of membrane proteins.
Specifications:
Purity (HPLC): >98%
Appearance: White solid crystals
Water: <5%
C32H58N2O8S
MW = 630.87 g/mol
Application:
for preparation/isolation of membrane proteinsSource:
syntheticClassification:
Documents:
CertificateCategory List
Accessory Items
CHAPS is a nondenaturing zwitterionic detergent for membrane biochemistry, isoelectric focusing and two-dimensional electrophoresis. Useful for solubilizing membrane proteins and breaking protein-protein interactions. Its small micellar molecular weight (6150) and high critical micellar concentration (6-10 mM) allow it to be removed from samples by dialysis. It is also suitable for protein solubilisation for isoelectric focusing and two-dimensional electrophoresis. CHAPS is commonly used for non-denaturing (without urea) IEF and has been shown to give excellent resolution of some subcellular preparations and plant proteins. Commonly used concentrations for IEF are 2-4% (v/v).