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Product information "n-Dodecyl-ß-maltopyranoside (DDM), min. 99%"
Highly pure Dodecyl-ß-maltopyranoside (DDM). Detergent to solubilize membrane assoziated proteins. n-Dodecyl-β-D-maltoside (DDM), a water-soluble nonionic detergent, for isolation and stabilization of hydrophobic membrane proteins. n-Dodecyl-β-D-maltoside is a gentle detergent that preserves protein activity better than many other detergents, such as CHAPS or octyl-β-glucoside.
Specifications:
Assay (HPLC): min. 99%
Appearance: White solid crystals
Solubility (1g in 10mL H2O (30°C)): clear, colourless solution
Contaminants (HPLC): n-Dodecanol: max. 0.001%.
Chemical formula: C24H46O11
MW = 510.63 g/mol
Classification:
Documents:
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Source: NCBI PubMed
Accessory Items
Octyl glucoside (n-octyl-β-D-glucoside) is a detergent frequently used to solubilise integral membrane proteins for studies in biochemistry. It has become one of the most important detergents for purification of membrane proteins because it generally does not denature the protein and can readily be removed from final protein extracts. Above its critical micelle concentration of 0.7%, it was noted as the best detergent for improving selectivity of immunoprecipitation of phosphotyrosine modified proteins. This detergent has also been shown to rapidly inactivate infective HIV at concentrations above its CMC (about 0.7% (w/v)).
n-Dodecyl-ß-maltoside (DDM) >99.5% especially suitable for use in crystallography. n-Dodecyl-β-D-maltoside (DDM), is a water-soluble non-ionic detergent, for isolation and stabilization of hydrophobic membrane proteins. n-Dodecyl-β-D-maltoside is a gentle detergent that preserves protein activity better than many other detergents, such as CHAPS or octyl-β-glucoside. The protein-sparing properties of this high-purity DDM allow it to be used, for example, in nasal sprays, as the DDM leads to improved mucus clearance.